制药工程专业英语模拟试卷
Part APut the following into English (2’):
衍生物污染物代谢物
氨基酸化疗互变异构体
硫醇对称的分馏
重结晶多糖亲和力
Part BPut the following into Chinese (2’):
Microorganismanilinein vitro
Asymmetricamino acidchronic
Antiviralbacteriologistdisinfection
Intermediateinsulinvaccine
Part CTranslate the English paragraphs into Chinese: (15’ * 2)
1) Be careful when handing chloroform.It’s a toxic solvent, and you should not breathe it exceively or spill it
on yourself.When discarding spent tea leaves, do not put them in the sink because they will clog the drain.
Dispose of them in a waste container.
2) When tannins are extracted into hot water, the hydrolysable ones are partially hydrolyzed, meaning that free
gallic acid is also found in tea.The tannins, by virtue of their phenolic groups, and gallic acid by virtue of it’s
carboxyl groups , are both acidic.
Part D Cloze (2’)
ViasolventsappropriateintermediateimilarindustrialNevertheleobtainedpreferredthoroughvaluable
by total synthesis.Therefore knowledge of the synthetic routes is useful.Understanding also makes it poible to recognize
contamination .of the agents by intermediates and by- products.For the reason of effective quality control the
documentation on the
stimulation as well.
There are neitherstructural claes for all pharmaceutically active compounds nor preferred
reaction types.This implies that practically the whole field of organic and in part also organometallic chemistry is covered.a larger number of starting materials and intermediates are more frequently used,and so it
is useful to know the poibilities for their preparation from primary chemicals.For this reason it iscompounds used in synthetic procees leading to an enormous number of agents.For the most part chemicals are
way this is also true for the intermediates based on
aromatic compounds toluene,phenol and chlorobenzene.Further key compounds may be shown in a table which can be useful in tracing cro-relationships in syntheses.
In addition to the actual starting materials and intermediates solvents are required both as a reaction
medium and ,for purificationrecrystallization.Frequently used are methanol,ethanol,
isopropanol,butanol,acetone,ethyl acetate,benzene,toluene and xylene.To a leer extent diethyl ether,
tetrahydrofuran,glycol ethers,dimethylformamide (DMF) and dimethyl sulphoxide (DMSO) are used in special
reactions.